Antonio, a young architect, desperately takes a dying Rosario Tijeras, to a nearby hospital. The beautiful Rosario was shot four times by a hit man. While he waits for his beloved Rosario to be saved from the wounds, Antonio remembers how Rosario turned into the assassin Rosario Tijeras. And how he, a promising young man, turns her into his obsession - the woman of his dreams. Rosario is a beautiful teenager that lives with a gang war in her neighborhood. Antonio is an idealistic student who is surprised when Rosario gives him a provocative kiss in front of the school where she studies. That kiss and that encounter mark´s Antonio who from that moment on, dreams about Rosario and looks for her throughout the whole neighborhood, joined by his great friend, the handsome and seductive Emilio. The lives of Antonio and Rosario cross on many opportunities and the young man falls in love even more with the beautiful and wild girl that kissed him. Rosario, expelled from school for confronting her teacher with a pair of scissors, now works for a mobster called "El Papa", who dies by her hand when she executes him in revenge for the death of her best friend. This isn’t the first time that Rosario shows her warrior blood. Days before, she also had her revenge from the man that tried to rape her, giving birth to the myth of Rosario Tijeras. Emilio, Antonio and Rosario will create an impossible love triangle. Rosario can’t love... only kill.